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Disturbances in balance can cause various disease conditions

The disease is highly heritable with gene association studies implicating genes that encode polymorphisms in extracellular matrix (ECM) molecules (e.g., MMP, HSP70, NOS3) or ocular development (the Frizzled related MFRP protein, hepatocyte growth factor HGF)

Peng YX, Chen CZ, Luo D, Yu WJ, Li SP, Xiao Y, Yuan B, Liang S, Yao XR, Kim NH, Jiang H et al (2020) Carnosic acid improves porcine early embryonic development by inhibiting the accumulation of reactive oxygen species