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P2X7 cell death receptor activation and mitochondrial impairment in oxaliplatin-induced apoptosis and neuronal injury: cellular mechanisms and approach

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2017;130(8):927-936.e9 Morin L

A 2006 study published in the British Journal of Dermatology found that afamelanotide increased eumelanin production by 3.5-fold in Type I skin after 14 days of dosing, compared to 1.8-fold in Type III skin, because the baseline melanocyte density and receptor expression differ significantly between phenotypes