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The results suggested that the upregulation of miR-153-3p alleviated the reduction in cell viability caused by 6-OHDA and reduced the secretion of lactate dehydrogenase (LDH)

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Cartilage and bone damage in rheumatoid arthritis

MG-induced DNA damage plays a central role in initiating apoptosis.MG induces DNA strand breaks through the formation of adducts (e.g., MGdG) and cross-linking structures with DNA, activating the intracellular DNA damage response, and triggering apoptosis by cell cycle arrest when the damage exceeds the cellular ability to repair it (104)