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The BA-mediated neuroprotection was accompanied by the significant upregulation of a crucial cellular pathway particularly related to the antioxidant defense system and cell survival, the PI3K/Akt/Nrf2 signaling pathway, thereby increasing antioxidant enzyme levels (GSH, SOD, CAT) and reducing neuronal death

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Upstream iron metabolism genes (such as FPN, TFR1, and DMT1) can influence the occurrence and development of ferroptosis 25,26,27,28 , but how does the downstream pathway change

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10.1155/2018/7412304 95 HuY.HuangL.ShenM.LiuY.LiuG.WuY.et al (2019)