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TIER PLANS TIER 1 (5mg total) $195 total for 8-10 week supply Monthly cost breakdown: $78-$97 based on weekly dose Recommended if new to treatment or for those on 0.2-0.6mg/week TIER 2 (10mg total) $230 total for 8-10 week supply Monthly cost breakdown: $92-$115 based on weekly dose Recommended for those on 0.7-1.2mg/week TIER 3 (20mg total) $260 total for 8-10 week supply Monthly cost breakdown: $104-$130 based on weekly dose Recommended for those on 1.3mg/week and up TIER 4* (30mg total) $300 total for 8-10 week supply For patients approved to be on high dose therapy of 3-4mg per week Monthly cost breakdown: $120-$150 based on weekly dose TIER 5* (40mg total) $350 total for 8-10 week supply For patients approved to be on high dose therapy of 4-5mg per week Monthly cost breakdown: $140-$175 based on weekly dose Southend Pharmacy - Semaglutide/B6 Injection Up to 90 days BUD

There are very few experiments that have been undertaken with such dosages on humans

Scand J Gastroenterol 30:10771081 Colaert N, Helsens K, Martens L, Vandekerckhove J, Gevaert K (2009) Improved visualization of protein consensus sequences by iceLogo

Can genetic factors influence B12 metabolism and dosing needs

Matrix Biol 49:3760 Ehren J, Moron B, Martin E, Bethune MT, Gray GM, Khosla C (2009) A food-grade enzyme preparation with modest gluten detoxification properties