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Why NAD+ declines during aging: it's destroyed

doi: 10.3389/fimmu.2019.02983 62 TessemaM

Many of these placebo-controlled studies have demonstrated that folic acid supplementation improved symptoms in severely depressed patients, elderly depressed and demented patients, and those with major acute depression or schizophrenia, particularly in individuals with RBC folate levels below 453 nmol/L (46)