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Metabolic Shift In Hypoxia-Adapted CML Cells and Mechanisms Of Acquired Dasatinib Resistance Uncovered By Proteomic iTRAQ Profiling

J Am Coll Cardiol 57(16):16411649 Schultheiss HP, Fairweather D, Caforio ALP, Escher F, Hershberger RE, Lipshultz SE, Liu PP, Matsumori A, Mazzanti A, McMurray J, Priori SG (2019) Dilated cardiomyopathy

The activation of phospholipid incorporation into HDLP is one explanation that leads to an increase in HDLP levels in the blood serum of patients under the influence of CP (207)

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However, recent studies have suggested that its low bioavailability in the brain following oral administration, limits its usage and in long term, leads to liver damage (Qiu et al., 2016)