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2025 Mar 28;23(4):146

Systemic therapies Research priorities: XIIIXIV Adjuvant systemic treatment Research priorities: XV After curative-intent resection, relapse rates are high, reaching approximately 70% at 5 years 235,236

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Crucially, the researchers noted that the S-A-GSH molecule was rapidly deacetylated once inside the body, proving that the acetyl shield successfully protected the compound through the digestive tract and then efficiently released the intact, active glutathione directly into the intracellular environment where it is needed to combat oxidative stress

40 Interestingly, superoxide dismutase and catalase are increased in older humans, suggesting a compensatory response to oxidative stress