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4 ChoiH.OhD.KimM.CaiL.LeeJ.KimE.et al (2022)

PESTLE Analysis 4.5

Porpora MG, Brunelli R, Costa G, Imperiale L, Krasnowska EK, Lundeberg T, et al

Research has demonstrated that AGEs can trigger cellular senescence via several mechanisms, including the initiation of p21 in an oxidative stress-dependent manner, upregulation of p16 expression, inhibition of autophagy by diminishing PINK1/Parkin activity, and the promotion of inflammation in renal cells (Liu et al., 2014

If this genetic variant is present in your PlexusDx results, the following tests and reports are commonly used to explore it further: Genetic Tests: Blood Tests: Genetic Report: Frequently Asked Questions About Hot Flashes and CYP1B1 rs1800440 How do CYP1B1 rs1800440 effect alleles change the risk of long-lasting hot flashes