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Glutathione also helps the body metabolize nutrients from the foods we eat, aids energy production, and assists in the regulation of cellular processes, including those that control: And because it contains the sulfur-bearing amino acid cysteine, glutathione naturally binds to heavy metals like mercury (via glutathione S-transferase) and prevents them from entering the body's cells, where they can cause organ damage

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FPSZM1, a bloodbrainbarrierpermeable RAGE inhibitor, significantly attenuates HMGB1-mediated pulmonary inflammation and tissue injury in murine emphysema models, illustrating proof of concept for its use in fibrotic lung disease (159)