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Sleeping well, exercising regularly and only drinking alcohol in moderation (the liver uses glutathione as a detoxifier) are also important

The role of EGFR in suppressing oxidative stress markers in an animal model of Parkinsons disease has also been clarified by a recent study, using Lapatinib (LAP), an anti-cancer drug that acts by mediating oxidative stress, with proven neuroprotective effects in case of epilepsy 37 .They observed that LAP restored glutathione/glutathione peroxidase (GSH/GPx) through the suppression of p-EGFR/c-SRC/PKCII/PLC-/ACSL-4 and PTGS2 38

In bovine heart SMPs, it was shown that MDA formation induced by the addition of NADH or NADPH in the presence of ADP and Fe 3+ was inhibited by succinate, and the effect of succinate was further enhanced by antimycin A and KCN (311)

Bacterial elements such as LPS and amyloid protein curli have been shown to enhance -synuclein aggregation (176)

Barrier dysfunction increases epithelial permeability, enabling inflammatory cytokines to penetrate deeper tissues and exacerbate intraepithelial damage