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Importantly, this was the case also for acetyl-carnitine, which is synthesized in the muscle from carnitine and acetylCoA when mitochondrial acetylCoA is abundant and exceeds its usage by the tricarboxylic acid (TCA) cycle

Proteins involved in the binding and trafficking of iron ions in the cytosol, called cytosolic iron chaperones, have been identified and characterized in mammalian cells

PMID: 26186445

Abnormal apoptosis contributes significantly to developing cancer and limits the efficiency of standard cytotoxic treatments [22, 50, 51]

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