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doi: 10.3233/JAD-150484

The prognosis varies depending on the underlying cause of the deficiency and how severe the deficiency is

A recent study highlighted that the low levels of neurogenesis present in stress-induced depressed mice were rescued by upregulation of the mitochondrial antioxidant sirtuin 3, being a promising strategy to confer stress resilience and improve depressed behavior [119]

The 2024 Antioxidants journal study specifically confirmed anticancer activities of citrus peel essential oils including grapefruit, attributing these properties primarily to the limonene content