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In addition to the proteomic approach, we measured the GSH levels in the plasma samples at 3 months post infection in PCC and Conv groups

discussion 712-3

Long-term efficacy and safety data are needed to assess the durability of improved glycaemic control and weight loss, and to further elucidate the potential for adverse events of special interest such as diabetic retinopathy, cholelithiasis, thyroid medullary cancer and adverse pancreatic outcomes

In SLC7A11 high cancer cells, high glutamate export results in a partial depletion of intracellular glutamate, which then drives cells through the relief of feedback inhibition to take up more glutamine as well as to activate glutaminase for glutamate replenishment, leading to glutamine dependency in SLC7A11 high cancer cells (Fig

doi: 10.1007/PL00007758 10 SurmeierDJObesoJAHallidayGM