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A biliary HCO 3 umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes

10.1155/2015/392360 70 MoiP.ChanK.AsunisI.CaoA.KanY

Aberrant transferrin and ferritin upregulation elicits iron accumulation and oxidative inflammaging causing ferroptosis and undermines estradiol biosynthesis in aging rat ovaries by upregulating NF-b-Activated inducible nitric oxide synthase: first demonstration of an intricate mechanism

Patients with severe forms of COVID-19 infection characterized by a hyperinflammatory state due to the cytokine storm may develop an acute hypothalamus/pituitary/thyroid axis dysfunction that may cause both acute hypothyroidism and immune-mediated damage (127)