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Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21

Avoid: Cooking glutathione-rich foods at high temperatures destroys its potency

[DOI] [PMC free article] [PubMed] [Google Scholar] 629.Joseph S., Nallaswamy D., Rajeshkumar S., Dathan P., Ismail S., Jacob J., Rasheed N

At intermediate concentrations, the extract maintained moderate activity, showing an absorbance of 46.8 0.002% at 125 g/mL, which then gradually decreased to 9.2 0.003% at 1.95 g/mL

in glioblastoma multiforme (GBM) cells, it activates AMPK, thereby inhibiting the downstream mTOR expression, and thus upregulating p53/p21 to block G1 progression ( in vitro and in vivo (Kim KN