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Fatigue and arthralgias are currently the most common HC symptoms

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Guri et al , 2017

Typically, these MRI abnormalities are found in the posterior columns, but abnormalities may also be found in the cerebral white matter and, rarely, in other locations, such as the globus pallidus (52

So much so, that the recent National Vascular Disease Prevention Alliance guidelines for management of cardiovascular disease recommend that blood triglyceride levels should be below a certain concentration (two milligrams per deciliter)