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3301-A ALCOHOL AND THE LIVER PHENOTYPE OF ADULTS WITH ALPHA-1 ANTITRYPSIN DEFICIENCY Malin Fromme 1 , Carolin Victoria Schneider 2 , Nurdan Guldiken 1 , Samira Amzou 1 , Yizhao Luo 1 , Monica Pons 3 , Joan Genesca 3 , Marc Miravitlles 4 , Katrine Holtz Thorhauge 5 , Johan Waern 6 , Kai M

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Activities of the control enzymes GSH peroxidase (GPx) and lactate dehydrogenase (LDH) were determined using published methods [22,23] with 1 mM sodium azide, 3.0 units of yeast GR (Sigma), 1 mM GSH, 0.02 mM DTT, 0.0007% (w/v) H 2 O 2 , and 100 M NADPH in the GPx assay and 10 M sodium pyruvate and 100 M NADPH in the LDH assay

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