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Estrogen treatment rescues ovariectomy-induced hepatic inflammation as well as systemic inflammation Loss of estrogen has been linked to activation of inflammatory pathways, specifically in postmenopausal women where this is prominent with increased emergence of liver disorders and cardiovascular diseases 66,67,68,69,70

Provides Cell-Protective Effect By lowering oxidative stress, glutathione helps protect: Nerves Kidneys Eyes Blood vessels Helps Reduce Diabetic Complications Oxidative stress is linked to: Neuropathy Retinopathy Kidney damage In studies, glutathione has shown protective effects against these complications

Aberrantly activated glial cells exacerbate neuroinflammation and influence synaptic pruning processes, with complement C4-mediated synaptic phagocytosis playing a critical role

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Hippocampal CA 1 neuronal processes were imaged and measured as described above