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Although there were no statistically significant differences between the treatment groups for adverse events, numbers of subjects reporting adverse events, serious adverse events, treatment-related adverse events, and severe adverse events were all greater in the treatment group (Table 12)

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"SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy"

Drugs Under Experimental and Clinical Research 10: 107111, 1984 Garzya G, Amico RM