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Aggregated AGEs can activate the JNK, I-B kinase (IKK), NF-B, and TNF- pathways to trigger hypothalamic insulin and leptin resistance, resulting in hypothalamic dysfunction, imbalanced energy control, and subsequently elevated food consumption and body weight with obesity and metabolic syndromes 78

Local delivery, distribution, and anti-metastatic effects of si-PGC-1 LNP in metastatic bladder cancer To evaluate the uniform distribution of siRNA in a mouse bladder cancer model, we injected si-PGC-1 LNP into subcutaneous xenografts

The role of TNFalpha and lymphotoxin in demyelinating disease

PKR promotes EphA2 and other proteins degradation and is predictor of survival in lung cancer

Identification of oxeiptosis-associated lncRNAs and prognosis-related signature to predict the immune status in gastric cancer