chac1 er stress glutathione degradation Peroxidase 8 Suppression by Histone Deacetylase Inhibitors Enhances Endoplasmic Reticulum and Cell Death by Oxidative Stress in Hepatocellular Carcinoma Cells Long noncoding RNA GDIL acts

Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2: Cell Reports Regulation of ChaC1. Oxidative and ER stress, and viral infection Download Scientific Diagram

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