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Excessive Glu uptake disrupts ionic balance, leading to astrocytic depolarization and influx of extracellular water, transforming the morphology of astrocytes toward the polarized A1 phenotype and promoting the central sensitization and NP (175)

Either size reduction of CdSe QDs or incorporation of Zn into CdSe QDs can lead to the increase in bandgap energies

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Critically evaluating only high quality randomised controlled trials it is still currently not possible to make strong clinical recommendations for the use of any modality, with little certainty in the current evidence base

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