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28,31 Studies have suggested that MAT reduces overdose mortality by 3- to 4-fold, reduces the incidence of HIV and hepatitis-C transmission by half, doubles adherence to HIV antiviral therapy, and reduces drug-related crime

British Journal of Nursing, 23(7), 376-381

Unlocking potential

Bloomfield, M

33,34 JNK translocates to mitochondria, binds to SH3 homologyassociated Brutons tyrosine kinase (BTK) binding protein (Sab) on the mitochondrial membrane, and subsequently inactivates a proto-oncogene tyrosine-protein kinase (Src) in mitochondria, eventually leading to the dysfunction of the ETC and the increased release of reactive oxygen species (ROS)