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Rather, it is better to think of it this way

doi: 10.1016/j.apsb.2020.12.020 267

Its not just a toss on the outside and he outruns everybody

10.1023/a:1012160102740 248 SchregelJ.Schulze HolthausenJ.SciasciaQ

The interaction of the p53-DBD with the Bax RE results in DNA deformation, and its partial disordering around the spacer regions allows p53-DBD to unwind and compress this region to promote proteinprotein interactions