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An estimated 20-30% of adults report significant needle phobia, and this fear prevents many individuals who would benefit from GLP-1 therapy from starting treatment

[41] : 973 Breast milk B 12 decreases over months of nursing in both well-nourished and vitamin-deficient mothers

[56] [57] Low levels of serum vitamin B 12 may be caused by other factors than B 12 deficiency, such as folate deficiency, pregnancy, oral contraceptive use, haptocorrin deficiency, and myeloma

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The two approaches answer different research questions and use different dosing conventions