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In addition, as an epigenetic modification, DNA methylation can be involved in disease progression and serve as a marker of environmental exposures, such as tobacco smoking, lipid peroxidation, and inflammation ( GSTA4 promoter, which contains antioxidant response elements, may act as an adaptive mechanism through which they are transcriptionally activated during exposure to lipid peroxidation of the vascular wall in IA patients ( GSTA4 methylation may serve as a biomarker of vascular impairment in patients with IA

Note: Individual variation is significant and depends on baseline skin condition, formulation concentration, application frequency, and individual genetic factors affecting collagen turnover rates

doi: 10.1159/000494547 88 ChoYParkMNChoiMUpadhyayTKKangHNOhJMet al

This means its capable of inhibiting bacterial growth

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