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Int J Mol Sci 25(10):5395 Dixit Y, Panda S, Kar A (2008) Lagenaria siceraria peel extract in the regulation of hyperthyroidism, hyperglycemia and lipid peroxidation in mice

Quando un tessuto viene danneggiato da lesioni, infiammazione o stress ossidativo le proteine della matrice extracellulare (in particolare collagene e SPARC) vengono degradate, rilasciando frammenti peptidici tra cui il GHK