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As 2 O 3 treatment was shown to have a dual effect on APL cells, with low arsenic concentration (0.250.50 mM) favoring APL cell differentiation and high concentrations (12 mM) inducing apoptosis (programmed cell death)

PPAR- is distributed in metabolically active tissues including liver, most prominently in hepatocytes [10, 11]

We thank Christopher Koscher for his assistance with protein expression and purification and Florian Grebien for help with establishing the RPE-1 cell lines stably expressing p53 and p53 mutants

Computational insights into missense mutations in HTT gene causing Huntingtons disease and its interactome networks

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