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Glutathione-based gold NCs (GSH-AuNCs) are protected by a small peptide compared to the large albumin and thus exhibit small hydrodynamic diameter that enable renal excretion 19,20

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Further testing of antioxidative agents on these models would help to evaluate the safety and effectiveness of such treatment

For example, curcumin-loaded electrospun PCL scaffolds have demonstrated sustained antioxidant release, reduced expression of pro-inflammatory cytokines, and enhanced collagen type I deposition in preclinical tendon defect models (Yoshikawa et al., 2025

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