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Description

Mechanistically, NNMT suppression increased adipose SAM and NAD, upregulated polyamine flux enzymes (ODC, SSAT), and altered histone methylation consistent with a shift toward oxidative metabolism [2]

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5Amino-1MQ 5-Amino-1MQ is a small-molecule compound targeting the NNMT pathway, and its currently being studied for its role in cellular metabolism, energy regulation, and adipocyte-related biochemical models

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