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J Dig Dis 11(6):352357 Kumar M, Kaur P, Chandel M, Singh AP, Jain A, Kaur S (2017) Antioxidant and hepatoprotective potential of Lawsonia inermis L

Indeed, inflammation begins in adipose tissue and gradually spreads to adjacent sites such as skeletal muscle and liver until a systemic, low-grade inflammatory state, also known as metabolic inflammation, develops and fails to resolve (156)

Disease activity in UC is typically characterized by a pattern of relapses and remission, and remission is marked by alternating phases of active symptoms and clinical quiescence [3, 4]