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The trial randomised 380 subjects on stable treatment with levodopa without motor complications to double-blind adjunct therapy with either 50 mg of opicapone or placebo for 24 weeks and offered transition into a 52-week extension on open-label treatment with 50 mg of opicapone for all participants [130]

Br J Anaesth 92:475484

Walker, B

Predstavte si L-karnitn ako vkonn motor funguje ovea lepie, ke je zmysluplne vyaen a energia je vyuit na nejak el

Academic and industrial efforts have progressively advanced from single-tissue to multi-tissue and multi-organ OoC systems, converging toward autologous OoC (aOoC) platforms that can (i) capture patient-specific immunopathophysiology with higher fidelity, (ii) potentially complement and, in specific contexts, reduce reliance on animal models, and (iii) directly inform immunotherapy development and therapeutic decision-making within precision medicine