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We discovered an increase in mitochondrial mass, spare respiratory capacity (SRC)both considered hallmarks of T mem cellsand, indeed, an enrichment of T memory cell formation in vivo and in vitro (van der Windt et al , 2012, 2013)

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The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

The chloroform phase was discarded after separation, as mentioned earlier ( The 3,3-diaminobenidine (DAB) assay was performed following the method mentioned earlier (Thordal-Christensen et al., 1997) to detect the H 2 O 2 accumulation

Mitochondria, as the core source and main target of ROS [449], their functional damage will further form a positive feedback loop of ROS generation - mitochondrial damage, causing energy metabolism disorders and inducing mitochondria to release pro-apoptotic factors such as cytochrome C, ultimately leading to neuronal apoptosis [450]