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Target antigen density governs the efficacy of anti-CD20-CD28-CD3 chimeric antigen receptor-modified effector CD8+ T cells

16 These biologics have proven efficacy, safety, and tolerability for the prevention and treatment of both episodic and chronic migraine in phase II and phase III randomized, placebo-controlled clinical trials

Intravenous synthetic peptide MBP8298 delayed disease progression in an HLA class II-defined cohort of patients with progressive multiple sclerosis: results of a 24-month double-blind placebo-controlled clinical trial and 5 years of follow-up treatment

Indirect calorimetric system For 48 h, at the end of the ASO treatment, animals were analyzed for Energy Expenditure (EE, kcal/h), Respiratory Quotient (RQ, VCO 2 /VO 2 ) and Locomotor Activity (LA) using an indirect calorimetric system (LabMaster