glutamine glutathione precursor drives synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines Glutamine metabolism and optimal immune

Despite the likely absence of SGLT2 in the myocardium, direct myocardial mechanisms of SGLT2i have been identified or proposed that may affect mitochondrial function

Theoretical concerns include the possibility that broad telomerase induction could, over very long horizons, lower the threshold for transformation in pre-malignant clones

(2012) revealed during postmortem examination of GLP intoxication cases that toxic effects were caused by their ability to erode tissues including mucous membranes and linings of the gastrointestinal and respiratory tracts

However, decreased GSH levels suggest a potentially altered antioxidant defense system

doi: 10.1158/2159-8290.cd-17-1461 14 PerilloBDi DonatoMPezoneADi ZazzoEGiovannelliPGalassoGet al