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g i ) Representative whole dorsal striatal images of NPY immunofluorescence from Trkb Penk-WT control ( g ), Trkb Penk-KO mutant injected at 3 M with Gsto2 -shRNA ( h ) or scrambled-shRNA in the striatum ( i ) and analysed at 15 W

TABLE 4 Impact of 6-OH-DA and D 2 agonists on the P450 activity

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Based on above findings, we summarized the metabolic characteristics of different types of DM and proposed the potential mechanism of dysregulation of serum metabolites in the pathogenesis of DM progression, as shown in Table 2 and Figure 5