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Bernth J, Fldesi D (1992) Sea buckthorn ( Hippophae rhamnoides L.)

The NLRP3 inflammasome promotes renal inflammation and contributes to CKD

Banach M, et al

Its important to note this study was observational, not a randomized controlled trial

These models are validated by their ability to reproduce a diversity of new experimental results, and can be used as platforms for in-silico experimentation to determine the underlying mechanisms that give rise to the behavior seen in the clinic and experiments