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Iosifescu DV, Jones A, OGorman C, Streicher C, Feliz S, Fava M, Tabuteau H, et al

Evason K, Collins JJ, Huang C, Hughes S, Kornfeld K

Prostate 80 , 481490 (2020)

Particularly darker pigmentation on the face, forearms, and shoulders compared to the torso

Previous structural studies have uncovered the open and closed conformations of ME2, which correspond to the enzymes inactive and active states, respectively