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Involvement of TRPA1 channels in the etiology of pain processes has not been fully clarified yet, although there are some reports on TRPA1 activation-induced pain processes such as diabetic peripheral pain (Andersson et al., 2015

Currently, a large number of people travel from plain areas to high altitude areas for tourism, work, sports competitions and performing tasks

TABLE 1 Age-related changes in individual cellular compartments

Either way, we would like to see a great deal more research into the role of B12 and sleep quality among both older and younger adults

Our data illustrate that this relationship is not straightforward