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Metabolic reprogramming involves a series of complex metabolic changes, including increased nutrient intake, enhanced glycolytic metabolism, altered amino acid metabolism, abnormal redox homeostasis, and aberrant fatty acid oxidation (Rodriguez et al., 2019

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Nat Rev Immun 9(5):313323 Collins SM, Bercik P (2009) The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease

serrata and many other medicinal plants contain phytochemicals such as quercetin, curcumol, rutin, isoquercetin, daidzin, boswellic acid, kaempferol, saponins, beta-caryophyllene etc