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In normal therapeutic doses, this toxic metabolite is quickly detoxified in Phase II through conjugation, where it binds with glutathione, a substance naturally produced by the liver

In general, hydrophilic amino acids contribute to the formation of a hydrophobic pocket in the H-site adjacent to the GSH-binding site (Figure 3B&C) [80, 85]

Exosomal miR-146a contributes to the enhanced therapeutic efficacy of Interleukin-1-Primed mesenchymal stem cells against sepsis

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