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In multivariate analyses controlled for age, duration of diabetes, and glycosylated haemoglobin (HbA1c) level, metformin therapy was associated independently with worse neuropathic symptoms

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The supplement has been used in folk medicine for hundreds of years to treat prostate and bladder infections due to its purported diuretic effects meaning its ability to increase urine output

Each patient, before treatment and upon completion of the study was scored with the HouseBrackmann scale, as well as a Facial Disability Index score (Table 1)