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[DOI] [PubMed] [Google Scholar] 31.Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial

Entacapone is a specific peripheral catechol- O -methyltransferase inhibitor approved by the US FDA in 1999 to treat patients with advanced Parkinsons disease as an adjuvant drug