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While age was associated with clinical symptoms, there was very little association between MMA levels and other biochemical parameters or clinical symptoms, including neurological symptoms

Seek emergency medical attention (call 999) if you experience: Difficulty breathing or swallowing Swelling of the face, lips, tongue, or throat Widespread rash or hives developing rapidly Severe dizziness or feeling faint Chest tightness or wheezing Anaphylaxis to hydroxocobalamin is uncommon but documented in the product information

Pain scores (VAS, WOMAC) showed numerical but not statistically significant improvements in most trials

Cerebrolysin has been shown to have neurotrophic effects similar to those of nerve growth factors, thereby stimulating peripheral and central neurons