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The results of Look AHEAD do not row against the implementation of lifestyle changes in patients with type 2 diabetes

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Ann Cardiothorac Surg 1(4):497-501, 2012

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In contrast, this treatment significantly downregulates the expression of cholesteryl esters (CEs) and TAGs by inhibiting the de novo synthesis of cholesterol and fatty acids, as demonstrated by isotope-tracing experiments and the downregulating effects of SREBF2 and ACLY expression 106

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