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Potential Side Effects Water retention (GH-related peptides) Joint stiffness or tingling (GH-related peptides) Lethargy (in some sensitive users) Increased appetite (MK-677 in particular) Injection site irritation (rare with proper technique) Legal Disclaimer Peptides such as BPC-157, TB500, and various growth hormone secretagogues are not approved by the FDA for general performance or cosmetic use