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62 Gene Expression: It upregulates the transcription of early growth response 1 (EGR1) and its co-regulator NAB2, which are critical for collagen type I deposition in connective tissues

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doi:10.4158/EP11009.OR 63

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In the case of decorin and lumican, the defect in fibrillogenesis is accompanied by clinically apparent skin hyperextensibility and a striking reduction in skin tensile strength