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doi: 10.1126/science.aav2588 Summary Keywords ammonia death, glutamine, CD8+ T cell, tumor microenvironment, immunotherapy Citation Du F, Xiao L, Guojun W, Dai Q, Li J, Zhao X, Zhang Q, Yang L, Liu Y, Hu Y, Wen B, Zhou J, Dai J, Zhang W and Zhang Z (2025) Glutamine metabolism and ammonia death: targeted modulation for enhanced cancer immunotherapy