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They can be constructed by using a wide range of substrates including organic (e.g., liposomes, micelles, hydrogels, etc.), 17,18,19 inorganic (e.g., metal/metal oxide particles, silica nanoparticles, quantum dots, etc.), 20,21 and biomass-derived materials (e.g., exosomes, cells, bacteria, etc.)

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For example, RNA sequencing technology allows researchers to analyze tens of thousands of gene expression changes simultaneously, facilitating the rapid identification of key genes related to the efficacy of Chinese medicine in treating depression [525, 526]

[DOI] [PubMed] [Google Scholar] (440).Zhang J-S